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What is Bute?

‘Bute’
– more correctly called phenylbutazone is one of the most commonly prescribed
medicines used in equine practice. It belongs to the group of drugs that are
known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). This is the same class
that includes Ibuprofen and Aspirin. Phenylbutazone is primarily used in horses
for its anti-inflammatory and analgesic effects. It is particularly useful for
the treatment of orthopaedic pain i.e. lameness, but is by no means confined to
this.

Equipalazone is one ‘brand name’
associated with phenlybutazone. It is usually adiministered in powder form
mixed with feed. Some horses don’t like the taste, so a paste can also be
obtained.
It is a prescription-only
medicine and should only be used only under veterinary supervision as it does
have some, all be it rare, side effects. Each case must be assessed by a
veterinary surgeon prior to treatment. Commonly it is used to treat arthritic
conditions and laminitis.

Arthritis is the commonest reason that
horses are given ‘bute’. This old hunter has some arthritis in its knee but is
able to work normally and comfortably on 1g of ‘bute’ per day.

This horse has arthritis of the coffin
joint – although no longer in work ‘bute’ helps it to enjoy a pain free
retirement.

‘Bute’
is one of the most effective treatments for chronic laminitis – as in this case
– but should not be used to mask problems. Good farriery is needed here to
restore normal foot balance.
Contrary to popular opinion
‘Bute’ is one of the safest drugs on the
market today. Literally millions of doses are administered to horses every year
– adverse reactions when ‘bute’ is used within normal dose rates are virtually
unheard of. When used over a prolonged period (i.e. years) ‘Bute’
can cause mild damage to the liver although this is uncommon. For any horses on
a repeat prescription e.g. for chronic lameness, it would be a good idea to do
an annual blood test.
‘Bute’
can also be associated with stomach and alimentary ulcers when used at high
dose rates. Signs of this can include weight loss or fluid swelling around the
abdomen and legs. If a horse shows any of these symptoms a veterinary surgeon
should be consulted.

Danilon (Suxibuzone) has recently been
developed for use in horses. It has a similar action to ‘bute’ but is easier to
administer (it tastes better!) and is less lightly to cause stomach ulcers.
Despite this, ‘Bute’ is a very safe drug which provides the gold standard
of pain relief in the horse. If you have any further questions please ask your
veterinary surgeon.
Equine Services

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